HIV-1 Accessory Proteins Impart a Modest Interferon Response and Upregulate Cell Cycle-Related Genes in Macrophages
HIV-1 infection of myeloid cells is associated with the induction of an IFN response.How HIV-1 manipulates and subverts the IFN response is of key interest for the design of therapeutics to improve immune function and mitigate immune dysregulation in people living with HIV.HIV-1 accessory genes function to improve viral fitness by altering host pat